IIIT Guwahati established I&E Cell in 2018 to promote entrepreneurship in the Institute. Students and faculty coordinators of IIITG, along with external members, oversee the I&E Cell activities. I&E Cell strives to kindle the spirit of entrepreneurship and encourage the students to think creatively and solve the issues related to entrepreneurship and society. It conducts several types of events including workshops, puzzles, and lectures, with the purview of introducing young leaders/aspirants to the models of social business. I&E Cell helps students interact with business leaders and to face challenges while dealing with social problems through a business perspective.